ISSN 1662-4009 (online)

ey0016.6-11 | DSD Reviews | ESPEYB16

6.11. Testis development

JA Makela , JJ Koskenniemi , HE Virtanen , J Toppari

Endocrine Reviews, Volume 40, Issue 4, August 2019, Pages 857–905doi: 10.1210/er.2018-00140. PMID: 30590466This encyclopedic article reviews the molecular and organizational events that take place during testicular development from the very early start, i.e. the development of the primordial germ cells before gastrulation and of the gonadal ridges at 3–4 week...

ey0019.15-8 | Assorted Conditions | ESPEYB19

15.8. Serum testosterone levels in 3-month-old boys predict their semen quality as young adults

Henriksen L Scheutz , Petersen J Holm , NE Skakkebaek , N Jorgensen , HE Virtanen , L Priskorn , A Juul , J Toppari , KM Main

J Clin Endocrinol Metab. 2022;107(7):1965-75. doi: 10.1210/clinem/dgac173.PubMed ID: 35323957Brief summary: This population-based birth cohort study related infancy serum testosterone concentrations at age 3 months to parameters of reproductive function at age 18 to 20 years in 259 males. Serum testosterone in infancy predicted adult total sperm counts, and other reproductive hormones and geni...

ey0020.5-4 | Clinical Guidance and Studies | ESPEYB20

5.4. Reproductive markers of testicular function and size during puberty in boys with and without a history of cryptorchidism

W Rodprasert , JJ Koskenniemi , HE Virtanen , S Sadov , A Perheentupa , H Ollila , J Albrethsen , A-M Andersson , A Juul , NE Skakkebaek , KM Main , J Toppari

Brief summary: This prospective longitudinal study compared serum reproductive hormone levels and testicular volume around the onset of puberty between cryptorchid and healthy boys.Congenital cryptorchidism is the most common congenital anomaly among newborn boys, and still little is known about pubertal testicular function and serum reproductive hormone levels during puberty in this population.Pubertal follow-up with clinical exam...